A vancomycin resistance-associated WalK(S221P) mutation attenuates the virulence of vancomycin-intermediate Staphylococcus aureus

Introduction: Vancomycin-intermediate Staphylococcus aureus (VISA) is typically associated with a decline in virulence. We previously reported a WalK(S221P) mutation that plays an important role in mediating vancomycin resistance in VISA XN108. Whether this mutation is implicated in bacterial virule...

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Bibliographic Details
Published in:Journal of Advanced Research
Main Authors: Yifan Rao, Huagang Peng, Weilong Shang, Zhen Hu, Yi Yang, Li Tan, Ming Li, Renjie Zhou, Xiancai Rao
Format: Article
Language:English
Published: Elsevier 2022-09-01
Subjects:
Staphylococcus aureus
Vancomycin resistance
WalKR
WalK(S221P)
Virulence
Agr system
Online Access:http://www.sciencedirect.com/science/article/pii/S2090123221002344

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http://www.sciencedirect.com/science/article/pii/S2090123221002344

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