Amorphous Solid Dispersions Layered onto Pellets—An Alternative to Spray Drying?

Spray drying is one of the most frequently used solvent-based processes for manufacturing amorphous solid dispersions (ASDs). However, the resulting fine powders usually require further downstream processing when intended for solid oral dosage forms. In this study, we compare properties and performa...

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發表在:	Pharmaceutics
Main Authors:	Marius Neuwirth, Sebastian K. Kappes, Michael U. Hartig, Karl G. Wagner
格式:	Article
語言:	英语
出版:	MDPI AG 2023-02-01
主題:	amorphous solid dispersions fluid bed spray drying pellet coating supersaturation release kinetics
在線閱讀:	https://www.mdpi.com/1999-4923/15/3/764