Glycyrrhiza Flavonoids Promote Osteoblast Proliferation and Differentiation by Activating Runx2 via the PI3K/AKT Signaling Pathway

In order to clarify the mechanism of action of licorice flavonoids in alleviating bone loss caused by osteoporosis, this study compared the effects of four glycyrrhiza flavonoids, naringenin, liquiritigenin, isoliquiritigenin, and licochalcone A, on osteogenic differentiation and mineralization by m...

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Bibliographic Details

Published in:	Shipin Kexue
Main Author:	CHU Hongdan, LIANG Zheng, XU Jingru, WANG Zhenhua, LI Gang, GAN Jing, XU Bo
Format:	Article
Language:	English
Published:	China Food Publishing Company 2025-10-01
Subjects:	mc3t3-e1 cells; liquiritigenin; osteogenesis; phosphatidylinositol-3-kinase/protein kinase b signaling pathway; zebrafish
Online Access:	https://www.spkx.net.cn/fileup/1002-6630/PDF/2025-46-20-019.pdf