Osteopontin Augments M2 Microglia Response and Separates M1- and M2-Polarized Microglial Activation in Permanent Focal Cerebral Ischemia

Background. Focal cerebral ischemia induces distinct neuroinflammatory processes. We recently reported the extracellular phosphor-glyco-protein osteopontin (OPN) to directly affect primary microglia in vitro, promoting survival while shifting their inflammatory profile towards a more neutral phenoty...

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出版年:	Mediators of Inflammation
主要な著者:	Anne Ladwig, Helene Luise Walter, Jörg Hucklenbroich, Antje Willuweit, Karl-Josef Langen, Gereon Rudolph Fink, Maria Adele Rueger, Michael Schroeter
フォーマット:	論文
言語:	英語
出版事項:	Wiley 2017-01-01
オンライン･アクセス:	http://dx.doi.org/10.1155/2017/7189421