Chromatin accessibility dynamics in colorectal cancer liver metastasis: Uncovering the liver tropism at single cell resolution

Tumor metastasis causes over 90% of cancer related death and no currently available therapies target it. However, there is limited understanding regarding the epigenetic regulation of genes during this complex process. Here by integrating single-cell ATAC-seq (scATAC-seq), single-cell RNA-seq (scRNA...

詳細記述

書誌詳細

出版年:	Pharmacological Research
主要な著者:	Shasha Li, Ming Yang, Shuaishuai Teng, Kequan Lin, Yumei Wang, Yanmei Zhang, Wei Guo, Dong Wang
フォーマット:	論文
言語:	英語
出版事項:	Elsevier 2023-09-01
主題:	Single-cell chromatin accessibility Colorectal cancer liver metastasis Liver tropism Tumor heterogeneity
オンライン･アクセス:	http://www.sciencedirect.com/science/article/pii/S1043661823002529