Nickel exposure induced endoplasmic reticulum stress by disturbing calcium homeostasis and triggered mitochondrial autophagy in domestic animal oocytes

Nickel, a heavy metal with industrial applications and as a feed additive for livestock, can adversely impact reproductive function and gamete quality when present in excessive amounts in the animal feed environment. In this study, the results indicate that nickel exposure hampers polar body extrusi...

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Bibliographic Details

Published in:	Ecotoxicology and Environmental Safety
Main Authors:	Chengkun Zhong, Shengkui Hou, Jing Guo, Jing Zhao, Jun Wang, Yi Fang, Hongyu Liu, He Ding, Xin Ma, Wenfa Lyu
Format:	Article
Language:	English
Published:	Elsevier 2025-09-01
Subjects:	Nickel Oocyte Endoplasmic reticulum Mitochondria Autophagy Calcium homeostasis
Online Access:	http://www.sciencedirect.com/science/article/pii/S0147651325010139