GRIN2B-related neurodevelopmental disorder: current understanding of pathophysiological mechanisms

The GRIN2B-related neurodevelopmental disorder is a rare disease caused by mutations in the GRIN2B gene, which encodes the GluN2B subunit of NMDA receptors. Most individuals with GRIN2B-related neurodevelopmental disorder present with intellectual disability and developmental delay. Motor impairment...

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Bibliographic Details

Published in:	Frontiers in Synaptic Neuroscience
Main Authors:	Shasta L. Sabo, Jessica M. Lahr, Madelyn Offer, Anika LA Weekes, Michael P. Sceniak
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2023-01-01
Subjects:	GRIN2B GluN2B (NMDA receptor subunit NR2B) dendrite development autism (ASD) neuron development disease variants
Online Access:	https://www.frontiersin.org/articles/10.3389/fnsyn.2022.1090865/full