HBV001: Phase I study evaluating the safety and immunogenicity of the therapeutic vaccine ChAdOx1-HBV

Background & Aims: Millions of people worldwide are infected chronically with HBV, which results in significant morbidity and mortality. Therapeutic vaccination is a strategy that aims to induce functional cure by restoring cellular immunity to HBV. Previously we have shown the candidate HBV...

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Bibliographic Details

Published in:	JHEP Reports
Main Authors:	Tamsin Cargill, Paola Cicconi, Anthony Brown, Louise Holland, Benaka Karanth, Kathryn Rutkowski, Emily Ashwin, Reena Mehta, Senthil Chinnakannan, Sarah Sebastian, Louise Bussey, Henrik Sorensen, Paul Klenerman, Thomas Evans, Eleanor Barnes
Format:	Article
Language:	English
Published:	Elsevier 2023-11-01
Subjects:	Hepatitis B Vaccine Chimpanzee adenovirus Shark invariant chain
Online Access:	http://www.sciencedirect.com/science/article/pii/S2589555923002161