Immunological Study of Reconstructed Common Ancestral Sequence of Adenovirus Hexon Protein

Aim: To reconstruct the ancestral sequence of human adenoviral hexon protein by combining sequence variations and structural information. And to provide a candidate hexon protein for developing new adenoviral vector capable of escaping the pre-existing immunity in healthy populations.Methods: The se...

詳細記述

書誌詳細

出版年:	Frontiers in Microbiology
主要な著者:	Yingchen Wang, Zhe Zhang, Lei Shang, Hong Gao, Xiqiao Du, Falong Li, Ya Gao, Guiyun Qi, Weiyuan Guo, Zhangyi Qu, Tuo Dong
フォーマット:	論文
言語:	英語
出版事項:	Frontiers Media S.A. 2021-10-01
主題:	human adenovirus protein structure evolutionary trace common ancestor reconstruction serum immunity
オンライン･アクセス:	https://www.frontiersin.org/articles/10.3389/fmicb.2021.717047/full