Fusobacterium mortiferum and its metabolite 5-aminovaleric acid promote the development of colorectal cancer in obese individuals through Wnt/β-catenin pathway by DKK2

Colorectal cancer (CRC) is one of the most prevalent cancers worldwide, with high incidence and mortality rates. An increasing body of research suggests that obesity is a significant risk factor for the development of CRC. Moreover, recent findings have highlighted the close association between the...

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Bibliographic Details
Published in:Gut Microbes
Main Authors: Jiaxin Deng, Jiawei Zhang, Mingli Su, Juan Li, Yuping Su, Qinghua Zhong, Jiancong Hu, Yongcheng Chen, Sen Liao, Dezheng Lin, Xuefeng Guo
Format: Article
Language:English
Published: Taylor & Francis Group 2025-12-01
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Online Access:https://www.tandfonline.com/doi/10.1080/19490976.2025.2502138