Allosteric amyloid catalysis by coiled coil fibrils

Abstract Amyloid-mediated catalysis of key biological reactions has recently attracted significant interest as this phenomenon may portend new functions for physiological and synthetic amyloid proteins. Here, we report an allosteric mechanism of catalytic amyloids, mediated via an unconventional coi...

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Bibliographic Details

Published in:	Nature Communications
Main Authors:	Sisira Mambram Kunnath, Elad Arad, Ran Zalk, Itamar Kass, Anat Shahar, Albert Batushansky, Hanna Rapaport, Raz Jelinek
Format:	Article
Language:	English
Published:	Nature Portfolio 2025-05-01
Online Access:	https://doi.org/10.1038/s41467-025-60379-z