The HIV Restriction Factor Profile in the Brain Is Associated with the Clinical Status and Viral Quantities

HIV-encoded DNA, RNA and proteins persist in the brain despite effective antiretroviral therapy (ART), with undetectable plasma and cerebrospinal fluid viral RNA levels, often in association with neurocognitive impairments. Although the determinants of HIV persistence have garnered attention, the ex...

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Bibliographic Details

Published in:	Viruses
Main Authors:	Nazanin Mohammadzadeh, Na Zhang, William G. Branton, Ouafa Zghidi-Abouzid, Eric A. Cohen, Benjamin B. Gelman, Jerome Estaquier, Linglong Kong, Christopher Power
Format:	Article
Language:	English
Published:	MDPI AG 2023-01-01
Subjects:	host restriction factors HIV-1 SIV RNA-seq transcriptomics machine learning
Online Access:	https://www.mdpi.com/1999-4915/15/2/316