Multi-omics profiling reveal cells with novel oncogenic cluster, TRAP1low/CAMSAP3low, emerge more aggressive behavior and poor-prognosis in early-stage endometrial cancer

Abstract The clinical heterogeneity of early-stage endometrial cancer (EC) is worthy of further study to identify high-quality prognostic markers and their potential role in aggressive tumor behavior. Mutation of TP53 was considered as an important primary triage in modified molecular typing for EC,...

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Bibliographic Details

Published in:	Molecular Cancer
Main Authors:	Xiaodan Mao, Xiaoyue Tang, Jingxuan Ye, Shuxia Xu, Yue Wang, Xianhua Liu, Qibin Wu, Xite Lin, Maotong Zhang, Jiangfeng Liu, Juntao Yang, Pengming Sun
Format:	Article
Language:	English
Published:	BMC 2024-06-01
Subjects:	TRAP1 CAMSAP3 TP53 Endometrial cancer Tumor microenvironment Proteomics
Online Access:	https://doi.org/10.1186/s12943-024-02039-2