Early cytokine signatures and clinical phenotypes discriminate persistent from resolving MRSA bacteremia

Abstract Background Staphylococcus aureus bacteremia (SAB) is a prevalent life-threatening infection often caused by methicillin-resistant S. aureus (MRSA). Up to 30% of SAB patients fail to clear infection even with gold-standard anti-MRSA antibiotics. This phenomenon is termed antibiotic-persisten...

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Bibliographic Details

Published in:	BMC Infectious Diseases
Main Authors:	Kristina V. Bergersen, Ying Zheng, Maura Rossetti, Felicia Ruffin, Harry Pickering, Rajesh Parmar, Gemalene Sunga, Liana C. Chan, David Gjertson, Vance G. Fowler, Michael R. Yeaman, Elaine F. Reed, the MRSA Systems Immunobiology Group
Format:	Article
Language:	English
Published:	BMC 2025-02-01
Subjects:	Staphylococcus aureus MRSA Cytokine signatures Clinical phenotypes Persistence
Online Access:	https://doi.org/10.1186/s12879-025-10620-3