Protection of stromal cell-derived factor-1 SDF-1/CXCL12 against proteases yields improved skin wound healing

SDF-1/CXCL12 is a unique chemotactic factor with multiple functions on various types of precursor cells, all carrying the cognate receptor CXCR4. Whereas individual biological functions of SDF-1/CXCL12 have been well documented, practical applications in medicine are insufficiently studied. This is...

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Bibliographic Details

Published in:	Frontiers in Immunology
Main Authors:	Rafaela Vaz Sousa Pereira, Mostafa EzEldeen, Estefania Ugarte-Berzal, Jennifer Vandooren, Erik Martens, Mieke Gouwy, Eva Ganseman, Jo Van Damme, Patrick Matthys, Jan Jeroen Vranckx, Paul Proost, Ghislain Opdenakker
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2024-08-01
Subjects:	SDF-1 CXCL12 proteolysis chemokine COAM wound healing
Online Access:	https://www.frontiersin.org/articles/10.3389/fimmu.2024.1359497/full