Into the Deep (Sequence) of the Foot-and-Mouth Disease Virus Gene Pool: Bottlenecks and Adaptation during Infection in Naïve and Vaccinated Cattle

Foot-and-mouth disease virus (FMDV) infects hosts as a population of closely related viruses referred to as a quasispecies. The behavior of this quasispecies has not been described in detail in natural host species. In this study, virus samples collected from vaccinated and non-vaccinated cattle up...

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Bibliographic Details

Published in:	Pathogens
Main Authors:	Ian Fish, Carolina Stenfeldt, Rachel M. Palinski, Steven J. Pauszek, Jonathan Arzt
Format:	Article
Language:	English
Published:	MDPI AG 2020-03-01
Subjects:	foot-and-mouth disease virus fmdv fmd quasispecies population dynamics within-host evolution bottleneck pathogenesis aphthovirus
Online Access:	https://www.mdpi.com/2076-0817/9/3/208