A Linear 19-Mer Plant Defensin-Derived Peptide Acts Synergistically with Caspofungin against Candida albicans Biofilms

Public health problems are associated with device-associated biofilm infections, with Candida albicans being the major fungal pathogen. We previously identified potent antibiofilm combination treatment in which the antifungal plant defensin HsAFP1 is co-administered with caspofungin, the preferred a...

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Bibliographic Details

Published in:	Frontiers in Microbiology
Main Authors:	Tanne L. Cools, Caroline Struyfs, Jan W. Drijfhout, Soňa Kucharíková, Celia Lobo Romero, Patrick Van Dijck, Marcelo H. S. Ramada, Carlos Bloch, Bruno P. A. Cammue, Karin Thevissen
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2017-10-01
Subjects:	fungal infections Candida antimicrobial peptides biofilms catheters
Online Access:	http://journal.frontiersin.org/article/10.3389/fmicb.2017.02051/full