Gene expression changes associated with resistance to intravenous corticosteroid therapy in children with severe ulcerative colitis.

Microarray analysis of RNA expression allows gross examination of pathways operative in inflammation. We aimed to determine whether genes expressed in whole blood early following initiation of intravenous corticosteroid treatment can be associated with response.From a prospectively accrued cohort of...

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Bibliographic Details

Published in:	PLoS ONE
Main Authors:	Boyko Kabakchiev, Dan Turner, Jeffrey Hyams, David Mack, Neal Leleiko, Wallace Crandall, James Markowitz, Anthony R Otley, Wei Xu, Pingzhao Hu, Anne M Griffiths, Mark S Silverberg
Format:	Article
Language:	English
Published:	Public Library of Science (PLoS) 2010-09-01
Online Access:	http://europepmc.org/articles/PMC2948001?pdf=render