Myeloproliferative neoplasms and the JAK/STAT signaling pathway: an overview

ABSTRACTMyeloproliferative neoplasms are caused by a clonal proliferation of a hematopoietic progenitor. First described in 1951 as 'Myeloproliferative Diseases' and reevaluated by the World Health Organization classification system in 2011, myeloproliferative neoplasms include polycythemi...

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Bibliographic Details

Published in:	Revista Brasileira de Hematologia e Hemoterapia
Main Authors:	Renata Mendes de Freitas, Carlos Magno da Costa Maranduba
Format:	Article
Language:	English
Published:	Elsevier 2015-10-01
Subjects:	Hematologic neoplasms Janus kinase 2 STAT transcription factors JAK2V617F mutation
Online Access:	http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-84842015000500348&lng=en&tlng=en