Oxygen-delivery nanoparticles enhanced immunotherapy efficacy monitored by granzyme B PET imaging in malignant tumors

Abstract Limited treatment response and inadequate monitoring methods stand firmly before successful immunotherapy. Recruiting and activating immune cells in the hypoxic tumor microenvironment is the key to reversing immune suppression and improving immunotherapy efficacy. In this study, biomimetic...

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Bibliographic Details

Published in:	Journal of Nanobiotechnology
Main Authors:	Xingyi Wang, Hanyi Fang, Wenzhu Hu, Yuan Feng, Zhangyongxue Zhou, Mengyan Hu, Dawei Jiang, Yongxue Zhang, Xiaoli Lan
Format:	Article
Language:	English
Published:	BMC 2025-03-01
Subjects:	Hypoxia Oxygen delivery nanoparticles Immunotherapy Granzyme B Positron emission tomography imaging
Online Access:	https://doi.org/10.1186/s12951-025-03257-6