Transposable element dynamics in glioblastoma stem cells: insights from locus-specific quantification

Abstract Background Glioblastoma, the most common primary malignant brain tumor, has a median survival of less than two years. This is due in part to a subpopulation of cells called glioblastoma stem cells (GSCs), which drive tumor recurrence. Transposable elements (TEs) are expressed at higher leve...

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Bibliographic Details
Published in:Mobile DNA
Main Authors: Mattia D. Pizzagalli, Yusuke Suita, Owen P. Leary, Nikos Tapinos
Format: Article
Language:English
Published: BMC 2025-09-01
Subjects:
Transposable elements
Transcription factors
Glioblastoma
Gene regulation
ERV
LINE
Online Access:https://doi.org/10.1186/s13100-025-00370-z

Internet

https://doi.org/10.1186/s13100-025-00370-z

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