Design, Synthesis and Biological Assessment of Rhodanine-Linked Benzenesulfonamide Derivatives as Selective and Potent Human Carbonic Anhydrase Inhibitors

A novel series of twenty-five rhodamine-linked benzenesulfonamide derivatives (<b>7a</b>–<b>u</b> and <b>9a</b>–<b>d</b>) were synthesized and screened for their inhibitory action against four physiologically relevant human (h) carbonic anhydrase (CA)...

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Bibliographic Details

Published in:	Molecules
Main Authors:	Baijayantimala Swain, Abrar Khan, Priti Singh, Vaibhav S. Marde, Andrea Angeli, Krishna Kartheek Chinchilli, Venkata Madhavi Yaddanapudi, Simone Carradori, Claudiu T. Supuran, Mohammed Arifuddin
Format:	Article
Language:	English
Published:	MDPI AG 2022-11-01
Subjects:	rhodanine carbonic anhydrase isoform selectivity benzenesulfonamide enzyme inhibition
Online Access:	https://www.mdpi.com/1420-3049/27/22/8028