Therapeutic potential of recombinant IL-22BP in psoriasis: suppression of IL-22/STAT3 signaling in mice

Abstract Psoriasis is a persistent immune-mediated inflammatory disorder that adversely affects the skin. Interleukin-22 (IL-22) is integral to the development and pathophysiology of psoriasis, and targeting IL-22 may serve as a promising therapeutic approach for treating the condition. IL-22 bindin...

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Bibliographic Details

Published in:	AMB Express
Main Authors:	Xiuze Chen, Tao Zeng, Fang Fang, Qinyu Tian, Yingying Li, Wenlin Zhou, Binqian Gong, Na Tian, Jizhou Zhang, Yechen Xiao
Format:	Article
Language:	English
Published:	SpringerOpen 2025-08-01
Subjects:	IL-22 rhIL-22BP-ABD Renaturation of inclusion body Psoriasis
Online Access:	https://doi.org/10.1186/s13568-025-01931-4