Seasonal childhood anaemia in West Africa is associated with the haptoglobin 2-2 genotype.

<h4>Background</h4>Anaemia is a major cause of morbidity and mortality for children in Africa. The plasma protein haptoglobin (Hp) binds avidly to free haemoglobin released following malaria-induced haemolysis. Haptoglobin polymorphisms result in proteins with altered haemoglobin-binding...

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Bibliographic Details

Published in:	PLoS Medicine
Main Authors:	Sarah H Atkinson, Kirk Rockett, Giorgio Sirugo, Philip A Bejon, Anthony Fulford, Maria A O'Connell, Robin Bailey, Dominic P Kwiatkowski, Andrew M Prentice
Format:	Article
Language:	English
Published:	Public Library of Science (PLoS) 2006-05-01
Online Access:	https://journals.plos.org/plosmedicine/article/file?id=10.1371/journal.pmed.0030172&type=printable