Rac1/WAVE2 and Cdc42/N-WASP Participation in Actin-Dependent Host Cell Invasion by Extracellular Amastigotes of Trypanosoma cruzi

This study evaluated the participation of host cell Rho-family GTPases and their effector proteins in the actin-dependent invasion by Trypanosoma cruzi extracellular amastigotes (EAs). We observed that all proteins were recruited and colocalized with actin at EA invasion sites in live or fixed cells...

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Bibliographic Details

Published in:	Frontiers in Microbiology
Main Authors:	Alexis Bonfim-Melo, Éden R. Ferreira, Renato A. Mortara
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2018-02-01
Subjects:	Trypanosoma cruzi extracellular amastigotes Rho GTPases actin host cell invasion
Online Access:	http://journal.frontiersin.org/article/10.3389/fmicb.2018.00360/full