A large, general and modular DARPin–apoferritin scaffold enables the visualization of small proteins by cryo-EM

Single-particle cryo-electron microscopy (cryo-EM) has emerged as an indispensable technique in structural biology that is pivotal for deciphering protein architectures. However, the medium-sized proteins (30–40 kDa) that are prevalent in both eukaryotic and prokaryotic organisms often elude the res...

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Bibliographic Details

Published in:	IUCrJ
Main Authors:	Xin Lu, Ming Yan, Yang Cai, Xi Song, Huan Chen, Mengtan Du, Zhenyi Wang, Jia'an Li, Liwen Niu, Fuxing Zeng, Quan Hao, Hongmin Zhang
Format:	Article
Language:	English
Published:	International Union of Crystallography 2025-05-01
Subjects:	cryo-em small proteins scaffolds darpin–apoferritin
Online Access:	https://journals.iucr.org/paper?S2052252525003021