Deciphering cellular signals in adult mouse sinoatrial node cells

Summary: Sinoatrial node (SAN) cells are the pacemakers of the heart. This study describes a method for culturing and infection of adult mouse SAN cells with FRET-based biosensors that can be exploited to examine signaling events. SAN cells cultured in media with blebbistatin or (S)-nitro-blebbistat...

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Bibliographic Details

Published in:	iScience
Main Authors:	Gopireddy R. Reddy, Lu Ren, Phung N. Thai, Jessica L. Caldwell, Manuela Zaccolo, Julie Bossuyt, Crystal M. Ripplinger, Yang K. Xiang, Madeline Nieves-Cintrón, Nipavan Chiamvimonvat, Manuel F. Navedo
Format:	Article
Language:	English
Published:	Elsevier 2022-01-01
Subjects:	Cell biology Functional aspects of cell biology Biology experimental methods
Online Access:	http://www.sciencedirect.com/science/article/pii/S2589004221016631