Coexistence of KRAS and BRAF Mutations in Colorectal Cancer: A case report supporting the concept of tumoral heterogeneity

The detection of KRAS and BRAF mutations is a crucial step for the correct therapeutic approach and predicting the epidermal growth factor receptor (EGFR)-targeted therapy resistance of colorectal carcinomas. The concomitant KRAS and BRAF mutations occur rarely in the colorectal cancers (CRCs) with...

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Bibliographic Details

Published in:	Cell Journal
Main Authors:	Pegah Larki, Ehsan Gharib, Mohammad Yaghoob Taleghani, Fatemeh Khorshidi, Ehsan Nazemalhosseini-Mojarad, Hamid Asadzadeh Aghdaei
Format:	Article
Language:	English
Published:	Royan Institute (ACECR), Tehran 2017-05-01
Subjects:	BRAF CRC EGFR KRAS
Online Access:	http://celljournal.org/journal/article/12070/download