Early human fetal lung atlas reveals the temporal dynamics of epithelial cell plasticity

Abstract Studying human fetal lungs can inform how developmental defects and disease states alter the function of the lungs. Here, we sequenced >150,000 single cells from 19 healthy human pseudoglandular fetal lung tissues ranging between gestational weeks 10–19. We capture dynamic developmental...

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Bibliographic Details
Published in:Nature Communications
Main Authors: Henry Quach, Spencer Farrell, Ming Jia Michael Wu, Kayshani Kanagarajah, Joseph Wai-Hin Leung, Xiaoqiao Xu, Prajkta Kallurkar, Andrei L. Turinsky, Christine E. Bear, Felix Ratjen, Brian Kalish, Sidhartha Goyal, Theo J. Moraes, Amy P. Wong
Format: Article
Language:English
Published: Nature Portfolio 2024-07-01
Online Access:https://doi.org/10.1038/s41467-024-50281-5