Renal tubular epithelial cell-derived Exosomal miR-330-3p plays a key role in fibroblast activation and renal fibrosis by regulating CREBBP

Abstract Background Renal tubular injury and activation of peripheral fibroblasts are hallmarks of chronic kidney disease (CKD), suggesting a close connection between the two cell types. Exosomes transport miRNAs and other substances to recipient cells. The involvement of exosome-mediated intercellu...

Full description

Bibliographic Details

Published in:	Stem Cell Research & Therapy
Main Authors:	Rong Dai, Meng Cheng, Chu-Yi Peng, Ze-Ping Cao, Hua Jin, Dong Wang, Yi-Ping Wang, Lei Zhang
Format:	Article
Language:	English
Published:	BMC 2025-04-01
Subjects:	Renal fibrosis Exosome Renal tubular epithelial cell Fibroblast MicroRNA
Online Access:	https://doi.org/10.1186/s13287-025-04338-x