The intrinsic role and mechanism of tumor expressed-CD38 on lung adenocarcinoma progression

Abstract It has been recently reported that CD38 expressed on tumor cells of multiple murine and human origins could be upregulated in response to PD-L1 antibody therapy, which led to dysfunction of tumor-infiltrating CD8+ T immune cells due to increasing the production of adenosine. However, the ro...

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Bibliographic Details
Published in:Cell Death and Disease
Main Authors: Long Gao, Yuan Liu, Xiaohong Du, Sai Ma, Minmin Ge, Haijun Tang, Chenfeng Han, Xin Zhao, Yanbin Liu, Yun Shao, Zhao Wu, Lianjun Zhang, Fang Meng, F. Xiao-Feng Qin
Format: Article
Language:English
Published: Nature Publishing Group 2021-07-01
Online Access:https://doi.org/10.1038/s41419-021-03968-2