Proteoglycan Sulphation in the Function of the Mature Central Nervous System

Chondroitin sulphate and heparan sulphate proteoglycans (CSPGS and HSPGs) are found throughout the central nervous system (CNS). CSPGs are ubiquitous in the diffuse extracellular matrix (ECM) between cells and are a major component of perineuronal nets (PNNs), the condensed ECM present around some n...

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Bibliographic Details

Published in:	Frontiers in Integrative Neuroscience
Main Authors:	James W. Fawcett, Jessica C. F. Kwok
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2022-05-01
Subjects:	chondroitin sulphate heparan sulphate perineuronal net memory plasticity neuroregeneration
Online Access:	https://www.frontiersin.org/articles/10.3389/fnint.2022.895493/full