Increased α‐tocopherol metabolism in horses with equine neuroaxonal dystrophy

Abstract Background Equine neuroaxonal dystrophy/equine degenerative myeloencephalopathy (eNAD/EDM) is an inherited neurodegenerative disorder associated with a vitamin E deficiency within the first year of life. Vitamin E consists of 8 isoforms metabolized by the CYP4F2 enzyme. No antemortem diagno...

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Bibliographic Details

Published in:	Journal of Veterinary Internal Medicine
Main Authors:	Erin N. Hales, Hadi Habib, Gianna Favro, Scott Katzman, R. Russell Sakai, Sabin Marquardt, Matthew H. Bordbari, Brittni Ming‐Whitfield, Janel Peterson, Anna R. Dahlgren, Victor Rivas, Carolina Alanis Ramirez, Sichong Peng, Callum G. Donnelly, Bobbi‐Sue Dizmang, Angelica Kallenberg, Robert Grahn, Andrew D. Miller, Kevin Woolard, Benjamin Moeller, Birgit Puschner, Carrie J. Finno
Format:	Article
Language:	English
Published:	Oxford University Press 2021-09-01
Subjects:	ataxia cytochrome P450 equine degenerative myeloencephalopathy genetics vitamin E
Online Access:	https://doi.org/10.1111/jvim.16233