Volumetric imaging of human mesenchymal stem cells (hMSCs) for non-destructive quantification of 3D cell culture growth.

The adoption of cell-based therapies into the clinic will require tremendous large-scale expansion to satisfy future demand, and bioreactor-microcarrier cultures are best suited to meet this challenge. The use of spherical microcarriers, however, precludes in-process visualization and monitoring of...

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Bibliographic Details

Published in:	PLoS ONE
Main Authors:	Oscar R Benavides, Holly C Gibbs, Berkley P White, Roland Kaunas, Carl A Gregory, Alex J Walsh, Kristen C Maitland
Format:	Article
Language:	English
Published:	Public Library of Science (PLoS) 2023-01-01
Online Access:	https://doi.org/10.1371/journal.pone.0282298