Isoflurane anesthesia precipitates tauopathy and upper airways dysfunction in pre-symptomatic Tau.P301L mice: Possible implication for neurodegenerative diseases

The postoperative cognitive decline resulting from volatile anesthesia is gaining acceptance as a major health problem. The common anesthetic isoflurane is suspected to precipitate neurodegeneration in Alzheimer's disease by unknown mechanisms. We previously validated that 8 month old Tau.P301L...

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發表在:	Neurobiology of Disease
Main Authors:	Clément Menuet, Peter Borghgraef, Nicolas Voituron, Christian Gestreau, Lies Gielis, Herman Devijver, Mathias Dutschmann, Fred Van Leuven, Gérard Hilaire
格式:	Article
語言:	英语
出版:	Elsevier 2012-04-01
主題:	Tauopathy Anesthesia Upper airways Memantine Isoflurane NMDA receptors
在線閱讀:	http://www.sciencedirect.com/science/article/pii/S0969996112000368