In Vivo Characterization of ONL1204, a Small Peptide Inhibitor of the Fas Receptor, as a Potential Neuroprotective Therapy for Geographic Atrophy and Dry Age-Related Macular Degeneration

<b>Background</b>: Age-related macular degeneration (AMD) is a major cause of irreversible vision loss in the developed world, and the approved products for geographic atrophy (GA), a late-stage form of dry AMD, have shown limited efficacy and require frequent administration. Therefore,...

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Bibliographic Details

Published in:	Biomedicines
Main Authors:	Andrew J. Kocab, Marisol Cano, Marianna Bacellar-Galdino, Jeffrey A. Jamison, William J. Brock, David N. Zacks, James T. Handa
Format:	Article
Language:	English
Published:	MDPI AG 2025-08-01
Subjects:	age-related macular degeneration geographic atrophy neuroprotection Fas CD95 animal models
Online Access:	https://www.mdpi.com/2227-9059/13/9/2052