Virus infection is controlled by hematopoietic and stromal cell sensing of murine cytomegalovirus through STING

Recognition of DNA viruses, such as cytomegaloviruses (CMVs), through pattern-recognition receptor (PRR) pathways involving MyD88 or STING constitute a first-line defense against infections mainly through production of type I interferon (IFN-I). However, the role of these pathways in different tissu...

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Bibliographic Details
Published in:eLife
Main Authors: Sytse J Piersma, Jennifer Poursine-Laurent, Liping Yang, Glen N Barber, Bijal A Parikh, Wayne M Yokoyama
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2020-07-01
Subjects:
cytomegalovirus
MyD88
STING
type I interferon
NK cell
Online Access:https://elifesciences.org/articles/56882

Internet

https://elifesciences.org/articles/56882

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