1α,25-Dihydroxyvitamin D3 reduces uropathogenic E. coli persistence in bladder epithelial cells by restoring lysosome acidification

This study aimed to examine the effect of 1α,25-dihydroxyvitamin D3 [1,25(OH)2D3] on the intracellular persistence of uropathogenic Escherichia coli. After establishing a cell infection model and conducting drug intervention, methods such as fluorescent probes, Western blot, and qPCR were used. The...

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Bibliographic Details

Published in:	Bangladesh Journal of Pharmacology
Main Authors:	Hao Yin, Yi Xue, Xin Wang
Format:	Article
Language:	English
Published:	Bangladesh Pharmacological Society 2025-04-01
Subjects:	1α,25-Dihydroxyvitamin D3 Epithelial cell E. coli Lysosome acidification Urinary bladder Uropathogenic
Online Access:	https://www.banglajol.info/index.php/BJP/article/view/79655