Deciphering the temporal heterogeneity of cancer-associated fibroblast subpopulations in breast cancer

Abstract Background Cancer-associated fibroblasts (CAFs) comprise a heterogeneous population of stromal cells within the tumour microenvironment. CAFs exhibit both tumour-promoting and tumour-suppressing functions, making them exciting targets for improving cancer treatments. Careful isolation, iden...

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Bibliographic Details

Published in:	Journal of Experimental & Clinical Cancer Research
Main Authors:	Freja Albjerg Venning, Kamilla Westarp Zornhagen, Lena Wullkopf, Jonas Sjölund, Carmen Rodriguez-Cupello, Pontus Kjellman, Mikkel Morsing, Morteza Chalabi Hajkarim, Kyoung Jae Won, Janine Terra Erler, Chris Denis Madsen
Format:	Article
Language:	English
Published:	BMC 2021-05-01
Subjects:	Cancer-associated fibroblast (CAF) CAF heterogeneity CAF subpopulations Flow cytometry analysis Breast cancer progression
Online Access:	https://doi.org/10.1186/s13046-021-01944-4