Protocol for a Wnt reporter assay to measure its activity in human neural stem cells derived from induced pluripotent stem cells

The canonical Wnt signaling is an essential pathway that regulates cellular proliferation, maturation, and differentiation during neurodevelopment and maintenance of adult tissue homeostasis. This pathway has been implicated with the pathophysiology of neuropsychiatric disorders and was associated w...

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Bibliographic Details

Published in:	Current Research in Neurobiology
Main Authors:	Cristine Marie Yde Ohki, Natalie Monet Walter, Michelle Rickli, José Maria Salazar Campos, Anna Maria Werling, Christian Döring, Susanne Walitza, Edna Grünblatt
Format:	Article
Language:	English
Published:	Elsevier 2023-01-01
Subjects:	Wnt signaling Neuropsychiatry Induced pluripotent stem cells Human stem cells Neural stem cells Reporter assay
Online Access:	http://www.sciencedirect.com/science/article/pii/S2665945X23000232