Puerarin, a key bioactive ingredient of Radix Puerariae, inhibits oxidative stress and protects against homocysteine-induced cardiac injury via PI3K/Akt/Nrf2/HO-1 signaling

Elevated plasma homocysteine (Hcy) levels are a major contributor to the risk factor for the developing cardiovascular diseases (CVDs). This study explored the protective efficacy of puerarin (Pue), a key bioactive ingredient derived from Radix Puerariae, against cardiac damage induced by Hcy, along...

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Bibliographic Details

Published in:	Journal of Agriculture and Food Research
Main Authors:	Shuang Jiang, Cong Li, Yanxing Han, Jiandong Jiang, Yuhong Wang
Format:	Article
Language:	English
Published:	Elsevier 2025-06-01
Subjects:	Puerarin Homocysteine Cardiac injury Oxidative stress PI3K/Akt/Nrf2/HO-1
Online Access:	http://www.sciencedirect.com/science/article/pii/S266615432500225X