Selenite selectively kills lung fibroblasts to treat bleomycin-induced pulmonary fibrosis

Background: Interstitial lung disease (ILD) treatment is a critical unmet need. Selenium is an essential trace element for human life and an antioxidant that activates glutathione, but the gap between its necessity and its toxicity is small and requires special attention. Whether selenium can be use...

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Bibliographic Details

Published in:	Redox Biology
Main Authors:	Jiun-Han Lin, Chen-Chi Liu, Chao-Yu Liu, Tien-Wei Hsu, Yi-Chen Yeh, Chorng-Kuang How, Han-Shui Hsu, Shih-Chieh Hung
Format:	Article
Language:	English
Published:	Elsevier 2024-06-01
Subjects:	Selenium Pulmonary fibrosis Apoptosis ROS Glutathione reductase Thioredoxin reductase
Online Access:	http://www.sciencedirect.com/science/article/pii/S2213231724001241