3, 3'5 Triiodo L thyronine induces apoptosis in human breast cancer MCF-7 cells, repressing SMP30 expression through negative thyroid response elements.

Thyroid hormones regulate cell proliferation, differentiation as well as apoptosis. However molecular mechanism underlying apoptosis as a result of thyroid hormone signaling is poorly understood. The antiapoptotic role of Senescence Marker Protein-30 (SMP30) has been characterized in response to var...

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Bibliographic Details
Published in:PLoS ONE
Main Authors: Pranati Sar, Rosalima Peter, Bandita Rath, Alok Das Mohapatra, Sandip K Mishra
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Online Access:http://europepmc.org/articles/PMC3110202?pdf=render