Essential function of the integrator complex in Kaposi’s sarcoma-associated herpesvirus lytic replication

ABSTRACT The integrator complex (INT) is an essential regulator of RNA biogenesis across evolution. Most current findings describe INT’s function in states of equilibrium, presenting a research gap in INT’s role in dynamic states, such as in infections and cancers. Viruses hijack cellular RNA machin...

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Bibliographic Details
Published in:Journal of Virology
Main Authors: Amy Nguyen, Tianqi Li, Conner Traugot, Kimberly Paulsen, Tiffany S. Nelson, Mingyi Xie, Zhe Ma
Format: Article
Language:English
Published: American Society for Microbiology 2025-09-01
Subjects:
integrator
Kaposi's sarcoma-associated herpesvirus
herpesviruses
lytic
reactivation
INTS11
Online Access:https://journals.asm.org/doi/10.1128/jvi.00266-25

Internet

https://journals.asm.org/doi/10.1128/jvi.00266-25

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