Clinical and biological features of PTPN2-deleted adult and pediatric T-cell acute lymphoblastic leukemia

Abstract: Protein tyrosine phosphatase nonreceptor type 2 (PTPN2) is a phosphatase known to be a tumor suppressor gene in T-cell acute lymphoblastic leukemia (T-ALL). Because the full clinicobiologic characteristics of PTPN2 loss remain poorly reported, we aimed to provide a comprehensive analysis o...

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Bibliographic Details

Published in:	Blood Advances
Main Authors:	Marion Alcantara, Mathieu Simonin, Ludovic Lhermitte, Aurore Touzart, Marie Emilie Dourthe, Mehdi Latiri, Nathalie Grardel, Jean Michel Cayuela, Yves Chalandon, Carlos Graux, Hervé Dombret, Norbert Ifrah, Arnaud Petit, Elizabeth Macintyre, André Baruchel, Nicolas Boissel, Vahid Asnafi
Format:	Article
Language:	English
Published:	Elsevier 2019-07-01
Online Access:	http://www.sciencedirect.com/science/article/pii/S2473952920306650