UPLC-Q-TOF-MS-based unbiased serum metabolomics investigation of cholangiocarcinoma

ObjectiveCholangiocarcinoma (CCA) is a highly aggressive malignancy, and early diagnosis remains challenging. Metabolic biomarkers are increasingly recognized as promising tools for the early detection of cancer. However, a comprehensive exploration of metabolic alterations in CCA, especially from a...

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Bibliographic Details

Published in:	Frontiers in Molecular Biosciences
Main Authors:	Xiaowei Wang, Xuefeng Xu, Ran Jia, Yuanhong Xu, Ping Hu
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2025-04-01
Subjects:	cholangiocarcinoma diagnosis unbiased serum metabolomics UPLC-Q-ToF-MS biomarker screen and identification
Online Access:	https://www.frontiersin.org/articles/10.3389/fmolb.2025.1549223/full