Tenecteplase Versus Alteplase in Acute Ischemic Stroke in Chinese Patients: Protocol for the ORIGINAL Study

Background Tenecteplase, a bioengineered variant of alteplase, is a new alternative thrombolytic agent. The ORIGINAL study aims to evaluate the efficacy and safety of tenecteplase versus standard care in Chinese patients with acute ischemic stroke within 4.5 hours of symptom onset. Methods This is a...

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Bibliographic Details

Published in:	Stroke: Vascular and Interventional Neurology
Main Authors:	Xia Meng, Shuya Li, Hongguo Dai, Guozhi Lu, Weiwei Wang, Fengyuan Che, Yu Geng, Minghui Sun, Xiyan Li, Yongjun Wang
Format:	Article
Language:	English
Published:	Wiley 2024-07-01
Subjects:	alteplase Chinese functional outcome ischemic stroke symptomatic intracerebral hemorrhage tenecteplase
Online Access:	https://www.ahajournals.org/doi/10.1161/SVIN.124.001363