Somatic evolutionary timings of driver mutations

Abstract Background A unified analysis of DNA sequences from hundreds of tumors concluded that the driver mutations primarily occur in the earliest stages of cancer formation, with relatively few driver mutation events detected in the late-arising subclones. However, emerging evidence from the seque...

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Bibliographic Details
Published in:BMC Cancer
Main Authors: Karen Gomez, Sayaka Miura, Louise A. Huuki, Brianna S. Spell, Jeffrey P. Townsend, Sudhir Kumar
Format: Article
Language:English
Published: BMC 2018-01-01
Subjects:
Driver mutation
Ubiquitous mutation
Private mutation
Somatic mutation
Online Access:http://link.springer.com/article/10.1186/s12885-017-3977-y

Internet

http://link.springer.com/article/10.1186/s12885-017-3977-y

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