Metabolic adaptation to chronic inhibition of mitochondrial protein synthesis in acute myeloid leukemia cells.

Recently, we demonstrated that the anti-bacterial agent tigecycline preferentially induces death in leukemia cells through the inhibition of mitochondrial protein synthesis. Here, we sought to understand mechanisms of resistance to tigecycline by establishing a leukemia cell line resistant to the dr...

詳細記述

書誌詳細

出版年:	PLoS ONE
主要な著者:	Bozhena Jhas, Shrivani Sriskanthadevan, Marko Skrtic, Mahadeo A Sukhai, Veronique Voisin, Yulia Jitkova, Marcela Gronda, Rose Hurren, Rob C Laister, Gary D Bader, Mark D Minden, Aaron D Schimmer
フォーマット:	論文
言語:	英語
出版事項:	Public Library of Science (PLoS) 2013-01-01
オンライン･アクセス:	http://europepmc.org/articles/PMC3592803?pdf=render