Reduced sensitivity of the ferroportin Q248H mutant to physiological concentrations of hepcidin

Ferroportin Q248H mutation has an allele frequency of 2.2–13.4% in African populations and is associated with a mild tendency to increased serum ferritin in the general population. Some investigators have reported that ferroportin Q248H is degraded after exposure to hepcidin in exactly the same mann...

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Bibliographic Details

Published in:	Haematologica
Main Authors:	Sergei Nekhai, Min Xu, Altreisha Foster, Ishmael Kasvosve, Sharmin Diaz, Roberto F. Machado, Oswaldo L. Castro, Gregory J. Kato, James G. Taylor, Victor R. Gordeuk
Format:	Article
Language:	English
Published:	Ferrata Storti Foundation 2013-03-01
Online Access:	https://haematologica.org/article/view/6601